HCSGD entry for HPS1
1. General information
| Official gene symbol | HPS1 |
|---|---|
| Entrez ID | 3257 |
| Gene full name | Hermansky-Pudlak syndrome 1 |
| Other gene symbols | HPS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005764 | Lysosome | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007040 | Lysosome organization | TAS | biological_process |
| GO:0007596 | Blood coagulation | IEA | biological_process |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IDA | cellular_component |
| GO:0030318 | Melanocyte differentiation | IEA | biological_process |
| GO:0031085 | BLOC-3 complex | IPI | cellular_component |
| GO:0032816 | Positive regulation of natural killer cell activation | IEA | biological_process |
| GO:0033299 | Secretion of lysosomal enzymes | IEA | biological_process |
| GO:0046983 | Protein dimerization activity | IPI | molecular_function |
| GO:0048069 | Eye pigmentation | IEA | biological_process |
| GO:0060041 | Retina development in camera-type eye | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4600668782 | 0.8222376126 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1632813787 |
| GSE13712_SHEAR | Up | 0.1230748391 |
| GSE13712_STATIC | Up | 0.0959633044 |
| GSE19018 | Down | -0.0001952070 |
| GSE19899_A1 | Down | -0.0357851604 |
| GSE19899_A2 | Up | 0.1276937188 |
| PubMed_21979375_A1 | Down | -0.2210984518 |
| PubMed_21979375_A2 | Up | 0.2403107746 |
| GSE35957 | Up | 0.1504754481 |
| GSE36640 | Up | 0.1284725971 |
| GSE54402 | Down | -0.1200062791 |
| GSE9593 | Up | 0.4349246890 |
| GSE43922 | Down | -0.3125597948 |
| GSE24585 | Up | 0.0225045425 |
| GSE37065 | Down | -0.0960961911 |
| GSE28863_A1 | Up | 0.0574147908 |
| GSE28863_A2 | Up | 0.1528175390 |
| GSE28863_A3 | Down | -0.1514307237 |
| GSE28863_A4 | Down | -0.0139460710 |
| GSE48662 | Up | 0.2108136544 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT043286 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048904 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
