HCSGD entry for APCS
1. General information
| Official gene symbol | APCS |
|---|---|
| Entrez ID | 325 |
| Gene full name | amyloid P component, serum |
| Other gene symbols | PTX2 SAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | NAS TAS | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0006953 | Acute-phase response | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA | cellular_component |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051082 | Unfolded protein binding | TAS | molecular_function |
| GO:0051131 | Chaperone-mediated protein complex assembly | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3199365526 | 0.9259948748 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0401433654 |
| GSE13712_SHEAR | Up | 0.1663844439 |
| GSE13712_STATIC | Up | 0.1456914809 |
| GSE19018 | Up | 0.0379868349 |
| GSE19899_A1 | Up | 0.1863513837 |
| GSE19899_A2 | Down | -0.0994443493 |
| PubMed_21979375_A1 | Down | -0.0333434069 |
| PubMed_21979375_A2 | Down | -0.0553927320 |
| GSE35957 | Up | 0.0784788481 |
| GSE36640 | Up | 0.0810757855 |
| GSE54402 | Up | 0.0451780528 |
| GSE9593 | Up | 0.1809712594 |
| GSE43922 | Up | 0.0143598511 |
| GSE24585 | Up | 0.0321061343 |
| GSE37065 | Down | -0.0668460646 |
| GSE28863_A1 | Up | 0.1459341844 |
| GSE28863_A2 | Down | -0.0485084072 |
| GSE28863_A3 | Up | 0.1162682056 |
| GSE28863_A4 | Up | 0.0729184124 |
| GSE48662 | Up | 0.7887142150 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Methyl 4,6-O-[(1r)-1-Carboxyethylidene]-Beta-D-Galactopyranoside | DB01651 | EXPT00869 |
| BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE | DB07579 | - |
| BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE | DB07580 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22156197 | Using gain- and loss-of-function models, we found that LXR signaling regulated the efficient clearance of senescent neutrophils by peripheral tissue APCs in a Mer-dependent manner |
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