HCSGD entry for HPD
1. General information
| Official gene symbol | HPD |
|---|---|
| Entrez ID | 3242 |
| Gene full name | 4-hydroxyphenylpyruvate dioxygenase |
| Other gene symbols | 4-HPPD 4HPPD GLOD3 HPPDASE PPD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003868 | 4-hydroxyphenylpyruvate dioxygenase activity | EXP ISS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006559 | L-phenylalanine catabolic process | IEA TAS | biological_process |
| GO:0006572 | Tyrosine catabolic process | ISS | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7114866380 | 0.6564876296 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0681317288 |
| GSE13712_SHEAR | Down | -0.0643348576 |
| GSE13712_STATIC | Down | -0.2082586825 |
| GSE19018 | Up | 0.1797358112 |
| GSE19899_A1 | Up | 0.0367614003 |
| GSE19899_A2 | Up | 0.0492225660 |
| PubMed_21979375_A1 | Down | -0.1582596128 |
| PubMed_21979375_A2 | Up | 0.0467948615 |
| GSE35957 | Down | -0.1106980814 |
| GSE36640 | Down | -0.0686649074 |
| GSE54402 | Down | -0.0209319074 |
| GSE9593 | Down | -0.0450767330 |
| GSE43922 | Up | 0.0186192543 |
| GSE24585 | Up | 0.0911341750 |
| GSE37065 | Down | -0.1714115469 |
| GSE28863_A1 | Down | -0.2224253571 |
| GSE28863_A2 | Up | 0.0993276293 |
| GSE28863_A3 | Up | 0.3177822216 |
| GSE28863_A4 | Down | -0.0184861982 |
| GSE48662 | Up | 0.2341864104 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Nitisinone | DB00348 | APRD01141 |
| (1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone | DB02850 | EXPT00327 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
