HCSGD entry for HOXD8
1. General information
| Official gene symbol | HOXD8 |
|---|---|
| Entrez ID | 3234 |
| Gene full name | homeobox D8 |
| Other gene symbols | HOX4 HOX4E HOX5.4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA NAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0008595 | Anterior/posterior axis specification, embryo | NAS | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0048705 | Skeletal system morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2321081076 | 0.4188229892 | 0.9156997153 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0574796972 |
| GSE13712_SHEAR | Down | -0.1916206765 |
| GSE13712_STATIC | Up | 0.1439853885 |
| GSE19018 | Up | 0.0966784336 |
| GSE19899_A1 | Up | 0.0924351383 |
| GSE19899_A2 | Up | 0.1825825525 |
| PubMed_21979375_A1 | Up | 0.0567063940 |
| PubMed_21979375_A2 | Down | -0.0793123325 |
| GSE35957 | Up | 0.7454928603 |
| GSE36640 | Up | 0.3588324904 |
| GSE54402 | Up | 0.1936597896 |
| GSE9593 | Down | -0.3111792119 |
| GSE43922 | Up | 0.1252511881 |
| GSE24585 | Up | 0.4346598745 |
| GSE37065 | Up | 0.0016361015 |
| GSE28863_A1 | Down | -0.1153963956 |
| GSE28863_A2 | Down | -0.0650398898 |
| GSE28863_A3 | Down | -0.2952164830 |
| GSE28863_A4 | Down | -0.3106855631 |
| GSE48662 | Down | -0.0127684693 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | MIRT002941 | Western blot | Functional MTI | 19418581 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT002941 | Luciferase reporter assay | Functional MTI | 15105502 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | 1 | hsa-miR-196a | 15105502 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
