HCSGD entry for HOXC6


1. General information

Official gene symbolHOXC6
Entrez ID3223
Gene full namehomeobox C6
Other gene symbolsCP25 HHO.C8 HOX3 HOX3C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048706Embryonic skeletal system developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94656745560.02016069300.99999024730.2750905132

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4334325868
GSE13712_SHEARDown-1.1840754461
GSE13712_STATICDown-0.2080930365
GSE19018Down-0.1570680952
GSE19899_A1Down-0.2093531961
GSE19899_A2Up0.0250192578
PubMed_21979375_A1Down-0.4314679164
PubMed_21979375_A2Up0.0093072367
GSE35957Down-0.5634621605
GSE36640Down-1.1816508028
GSE54402Down-0.2836318665
GSE9593Down-0.1573462198
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.4044842670
GSE28863_A2Down-0.2482503636
GSE28863_A3Down-0.0232368370
GSE28863_A4Down-0.1669346266
GSE48662Up0.2566434088

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017144MicroarrayFunctional MTI (Weak)18185580
hsa-miR-128-3pMIMAT0000424MIRT021916SequencingFunctional MTI (Weak)20371350
hsa-miR-27a-3pMIMAT0000084MIRT028721SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.