HCSGD entry for HOXB5
1. General information
| Official gene symbol | HOXB5 |
|---|---|
| Entrez ID | 3215 |
| Gene full name | homeobox B5 |
| Other gene symbols | HHO.C10 HOX2 HOX2A HU-1 Hox2.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | IEA | molecular_function |
| GO:0001205 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0045446 | Endothelial cell differentiation | IEA | biological_process |
| GO:0048704 | Embryonic skeletal system morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0082441245 | 0.9604244140 | 0.2352350649 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3341114731 |
| GSE13712_SHEAR | Up | 0.6573143692 |
| GSE13712_STATIC | Down | -0.3024743369 |
| GSE19018 | Up | 0.4804314340 |
| GSE19899_A1 | Up | 0.2106117632 |
| GSE19899_A2 | Up | 1.3927489347 |
| PubMed_21979375_A1 | Down | -0.4378456770 |
| PubMed_21979375_A2 | Up | 0.0031486696 |
| GSE35957 | Up | 0.0794692830 |
| GSE36640 | Up | 0.3087376568 |
| GSE54402 | Down | -0.1736876554 |
| GSE9593 | Up | 0.0343777172 |
| GSE43922 | Up | 0.0823049003 |
| GSE24585 | Up | 1.8847448349 |
| GSE37065 | Up | 0.0116845257 |
| GSE28863_A1 | Down | -0.0833160988 |
| GSE28863_A2 | Up | 0.5394531173 |
| GSE28863_A3 | Up | 0.5534377453 |
| GSE28863_A4 | Up | 0.1925598020 |
| GSE48662 | Up | 0.0548115526 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT006902 | Immunohistochemistry//Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22768238 |
| hsa-miR-429 | MIMAT0001536 | MIRT016641 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT020354 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT021075 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-141-3p | MIMAT0000432 | MIRT021658 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT024129 | Reporter assay | Functional MTI | 20005803 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
