HCSGD entry for HOXB2


1. General information

Official gene symbolHOXB2
Entrez ID3212
Gene full namehomeobox B2
Other gene symbolsHOX2 HOX2H Hox-2.8 K8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002011Morphogenesis of an epithelial sheetIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008015Blood circulationTASbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0009953Dorsal/ventral pattern formationIEAbiological_process
GO:0021569Rhombomere 3 developmentIEAbiological_process
GO:0021570Rhombomere 4 developmentIEAbiological_process
GO:0021612Facial nerve structural organizationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
GO:0048857Neural nucleus developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11654305310.08668653930.70016902370.5589604116

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4225138445
GSE13712_SHEARUp0.5917308452
GSE13712_STATICDown-0.0707387876
GSE19018Down-0.4106844268
GSE19899_A1Down-0.3949642352
GSE19899_A2Up0.6493568051
PubMed_21979375_A1Up0.4544228938
PubMed_21979375_A2Down-0.1233773603
GSE35957Down-1.4462177147
GSE36640Up0.1878316612
GSE54402Up0.3771865535
GSE9593Down-0.1311481823
GSE43922Down-0.0227779946
GSE24585Up1.5482932364
GSE37065Down-0.0941170566
GSE28863_A1Down-0.5253326714
GSE28863_A2Down-0.2825244163
GSE28863_A3Down-0.2689988449
GSE28863_A4Up0.0659501650
GSE48662Down-0.0360076603

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-17-3pMIMAT0000071MIRT050781CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.