HCSGD entry for HOXB1
1. General information
| Official gene symbol | HOXB1 |
|---|---|
| Entrez ID | 3211 |
| Gene full name | homeobox B1 |
| Other gene symbols | HCFP3 HOX2 HOX2I Hox-2.9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | NAS | biological_process |
| GO:0007389 | Pattern specification process | TAS | biological_process |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0021570 | Rhombomere 4 development | IEA | biological_process |
| GO:0021571 | Rhombomere 5 development | IEA | biological_process |
| GO:0021612 | Facial nerve structural organization | IEA | biological_process |
| GO:0021754 | Facial nucleus development | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0048646 | Anatomical structure formation involved in morphogenesis | IEA | biological_process |
| GO:0048704 | Embryonic skeletal system morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5528203564 | 0.7907676114 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0156625067 |
| GSE13712_SHEAR | Up | 0.1127069140 |
| GSE13712_STATIC | Down | -0.1167401437 |
| GSE19018 | Up | 0.0551128851 |
| GSE19899_A1 | Up | 0.0186065541 |
| GSE19899_A2 | Up | 0.0851592676 |
| PubMed_21979375_A1 | Down | -0.1939535542 |
| PubMed_21979375_A2 | Down | -0.0062164763 |
| GSE35957 | Up | 0.2785204197 |
| GSE36640 | Up | 0.0613084109 |
| GSE54402 | Up | 0.0333876420 |
| GSE9593 | Up | 0.1891276659 |
| GSE43922 | Up | 0.1275428677 |
| GSE24585 | Down | -0.2258858984 |
| GSE37065 | Up | 0.0286926017 |
| GSE28863_A1 | Down | -0.1088153023 |
| GSE28863_A2 | Down | -0.2556711135 |
| GSE28863_A3 | Up | 0.2030280798 |
| GSE28863_A4 | Up | 0.2496856544 |
| GSE48662 | Down | -0.0948034661 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018826 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030143 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
