HCSGD entry for HOXA11

1. General information

Official gene symbolHOXA11
Entrez ID3207
Gene full namehomeobox A11
Other gene symbolsHOX1 HOX1I
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001501Skeletal system developmentISSbiological_process
GO:0001656Metanephros developmentIEAbiological_process
GO:0001658Branching involved in ureteric bud morphogenesisISSbiological_process
GO:0001759Organ inductionIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005667Transcription factor complexISScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007275Multicellular organismal developmentISSbiological_process
GO:0007501Mesodermal cell fate specificationISSbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0009953Dorsal/ventral pattern formationISSbiological_process
GO:0009954Proximal/distal pattern formationIEAbiological_process
GO:0010720Positive regulation of cell developmentISSbiological_process
GO:0030326Embryonic limb morphogenesisISSbiological_process
GO:0032332Positive regulation of chondrocyte differentiationISSbiological_process
GO:0032993Protein-DNA complexISScellular_component
GO:0035115Embryonic forelimb morphogenesisIEAbiological_process
GO:0042733Embryonic digit morphogenesisIEAbiological_process
GO:0043234Protein complexISScellular_component
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0048589Developmental growthISSbiological_process
GO:0060272Embryonic skeletal joint morphogenesisIEAbiological_process
GO:0060351Cartilage development involved in endochondral bone morphogenesisISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34234659780.48904870260.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0060949632
GSE13712_SHEARUp0.1711886113
GSE13712_STATICDown-0.2222373162
GSE19018Up0.0314242579
GSE19899_A1Up0.0051967386
GSE19899_A2Up0.1942342942
PubMed_21979375_A1Up0.3278138354
PubMed_21979375_A2Up0.2821675442
GSE35957Down-0.2439925489
GSE36640Up0.0368243113
GSE54402Up0.1356322264
GSE9593Up0.0461502593
GSE43922Up0.0144841640
GSE24585Up0.7085401680
GSE37065Down-0.2605295096
GSE28863_A1Down-0.0389800589
GSE28863_A2Down-0.1063139484
GSE28863_A3Down-0.6094848828
GSE28863_A4Down-0.1114121182
GSE48662Up0.2574435585

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017072MicroarrayFunctional MTI (Weak)18185580
hsa-miR-769-3pMIMAT0003887MIRT039124CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041937CLASHFunctional MTI (Weak)23622248
hsa-miR-30d-5pMIMAT0000245MIRT047784CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-181a-5pMIMAT00002561hsa-miR-181a{Western blot}{Western blot}{overexpression by mature miRNA transfection}{underexpression by LNA antisense miRNA oligonucleotides}16489342
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.