HCSGD entry for HOXA7
1. General information
| Official gene symbol | HOXA7 |
|---|---|
| Entrez ID | 3204 |
| Gene full name | homeobox A7 |
| Other gene symbols | ANTP HOX1 HOX1.1 HOX1A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA IEA | biological_process |
| GO:0001525 | Angiogenesis | IEP | biological_process |
| GO:0001953 | Negative regulation of cell-matrix adhesion | IDA | biological_process |
| GO:0002686 | Negative regulation of leukocyte migration | IDA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IC IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA | molecular_function |
| GO:0045617 | Negative regulation of keratinocyte differentiation | IDA | biological_process |
| GO:0045656 | Negative regulation of monocyte differentiation | IDA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0048704 | Embryonic skeletal system morphogenesis | IEA | biological_process |
| GO:0048863 | Stem cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5226211656 | 0.0151258311 | 0.9999902473 | 0.2417285974 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0269847538 |
| GSE13712_SHEAR | Down | -0.3022312465 |
| GSE13712_STATIC | Down | -0.4022086131 |
| GSE19018 | Up | 0.3147242988 |
| GSE19899_A1 | Down | -0.4164413080 |
| GSE19899_A2 | Down | -0.8705793519 |
| PubMed_21979375_A1 | Down | -1.6522235554 |
| PubMed_21979375_A2 | Down | -0.5980740199 |
| GSE35957 | Up | 0.1273931371 |
| GSE36640 | Down | -2.4664243630 |
| GSE54402 | Down | -0.7864127155 |
| GSE9593 | Down | -0.2200027831 |
| GSE43922 | Down | -0.5949270192 |
| GSE24585 | Up | 1.0758885559 |
| GSE37065 | Up | 0.3431942110 |
| GSE28863_A1 | Down | -0.1457679797 |
| GSE28863_A2 | Up | 0.3154536707 |
| GSE28863_A3 | Up | 0.3081920722 |
| GSE28863_A4 | Down | -0.1081743771 |
| GSE48662 | Up | 0.1587034931 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | MIRT002940 | Western blot | Functional MTI | 19418581 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT002940 | Luciferase reporter assay | Functional MTI | 15105502 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT002940 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT002940 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038144 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049904 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | 3 | hsa-miR-196a | 15105502 | |||
| hsa-miR-196a-5p | MIMAT0000226 | 2 | hsa-miR-196a | 15105502 | |||
| hsa-miR-196a-5p | MIMAT0000226 | 1 | hsa-miR-196a | 15105502 | |||
| hsa-miR-196a-5p | MIMAT0000226 | 4 | hsa-miR-196a | 15105502 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
