HCSGD entry for ACACB

1. General information

Official gene symbolACACB
Entrez ID32
Gene full nameacetyl-CoA carboxylase beta
Other gene symbolsACC2 ACCB HACC275
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003989Acetyl-CoA carboxylase activityIDA IEAmolecular_function
GO:0004075Biotin carboxylase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006084Acetyl-CoA metabolic processIDA IEAbiological_process
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006633Fatty acid biosynthetic processIEAbiological_process
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006768Biotin metabolic processTASbiological_process
GO:0006853Carnitine shuttleTASbiological_process
GO:0009374Biotin bindingIEAmolecular_function
GO:0012505Endomembrane systemIEAcellular_component
GO:0014070Response to organic cyclic compoundIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0031325Positive regulation of cellular metabolic processTASbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051289Protein homotetramerizationIDAbiological_process
GO:2001295Malonyl-CoA biosynthetic processIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25132846400.78953929560.94120881811.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0299869664
GSE13712_SHEARDown-0.0130042719
GSE13712_STATICDown-0.0554251459
GSE19018Down-0.0765098735
GSE19899_A1Up0.1667245488
GSE19899_A2Down-0.4070118241
PubMed_21979375_A1Down-0.3955629030
PubMed_21979375_A2Up0.0937305815
GSE35957Down-0.1197955278
GSE36640Up0.0488041365
GSE54402Down-0.2212272830
GSE9593Down-0.4343331673
GSE43922Up0.0244105471
GSE24585Up0.6756368473
GSE37065Up0.1905575532
GSE28863_A1Up0.5904415810
GSE28863_A2Up0.3064156492
GSE28863_A3Up0.1703932761
GSE28863_A4Down-0.0080339717
GSE48662Up0.1930338388

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AdenineDB00173 NUTR00012 | EXPT00520
Soraphen ADB02859 EXPT02829
2-[4-(2,4-Dichlorophenoxy)Phenoxy]Propanoic AcidDB03781 EXPT01094
(2S)-2-(4-{[3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOXY)PROPANOIC ACIDDB07870 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019364MicroarrayFunctional MTI (Weak)17612493
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.