HCSGD entry for HOXA2

1. General information

Official gene symbolHOXA2
Entrez ID3199
Gene full namehomeobox A2
Other gene symbolsHOX1K
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001709Cell fate determinationIEAbiological_process
GO:0002076Osteoblast developmentIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007379Segment specificationIEAbiological_process
GO:0008045Motor neuron axon guidanceIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0009953Dorsal/ventral pattern formationIEAbiological_process
GO:0021568Rhombomere 2 developmentIEAbiological_process
GO:0021658Rhombomere 3 morphogenesisIEAbiological_process
GO:0035284Brain segmentationIEAbiological_process
GO:0042474Middle ear morphogenesisIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045665Negative regulation of neuron differentiationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048703Embryonic viscerocranium morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87538633030.00754088750.99999024730.1736590750

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1055601562
GSE13712_SHEARUp0.0210010145
GSE13712_STATICUp0.2693510588
GSE19018Down-0.1399588530
GSE19899_A1Down-0.1310754070
GSE19899_A2Down-1.6480941055
PubMed_21979375_A1Down-1.6631633374
PubMed_21979375_A2Down-0.9801651677
GSE35957Up0.1056282111
GSE36640Down-1.8807384659
GSE54402Down-1.5937565664
GSE9593Up0.1009102850
GSE43922Down-1.9796204858
GSE24585Up0.6589760267
GSE37065Up0.0273831618
GSE28863_A1Up0.0224991712
GSE28863_A2Up0.1288754553
GSE28863_A3Up0.0149347508
GSE28863_A4Up0.0149745833
GSE48662Down-0.1342158860

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017046MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.