HCSGD entry for ONECUT1

1. General information

Official gene symbolONECUT1
Entrez ID3175
Gene full nameone cut homeobox 1
Other gene symbolsHNF-6 HNF6 HNF6A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionISSmolecular_function
GO:0001889Liver developmentIEAbiological_process
GO:0001952Regulation of cell-matrix adhesionIEAbiological_process
GO:0002064Epithelial cell developmentIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006006Glucose metabolic processIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0006366Transcription from RNA polymerase II promoterISSbiological_process
GO:0007492Endoderm developmentIEAbiological_process
GO:0030183B cell differentiationIEAbiological_process
GO:0030335Positive regulation of cell migrationIEAbiological_process
GO:0030512Negative regulation of transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0031018Endocrine pancreas developmentTASbiological_process
GO:0042384Cilium assemblyIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045165Cell fate commitmentIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0048536Spleen developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35376799890.94281046310.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0612931917
GSE13712_SHEARDown-0.0381509695
GSE13712_STATICDown-0.0074278036
GSE19018Up0.1582184150
GSE19899_A1Down-0.0137103868
GSE19899_A2Up0.3594427092
PubMed_21979375_A1Up0.0511513816
PubMed_21979375_A2Up0.3190998150
GSE35957Down-0.0047745039
GSE36640Up0.1649617810
GSE54402Up0.0485224897
GSE9593Down-0.0276381221
GSE43922Up0.0556339477
GSE24585Up0.1049932177
GSE37065Up0.0003592747
GSE28863_A1Down-0.0652882554
GSE28863_A2Down-0.0072167324
GSE28863_A3Up0.2873541099
GSE28863_A4Up0.0992084912
GSE48662Down-0.0031178101

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.