HCSGD entry for HMGB3
1. General information
| Official gene symbol | HMGB3 |
|---|---|
| Entrez ID | 3149 |
| Gene full name | high mobility group box 3 |
| Other gene symbols | HMG-2a HMG-4 HMG2A HMG4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003690 | Double-stranded DNA binding | ISS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0006310 | DNA recombination | ISS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008301 | DNA binding, bending | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9993491889 | 0.0005324304 | 0.9999902473 | 0.0427259146 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1998823612 |
| GSE13712_SHEAR | Down | -0.3699685593 |
| GSE13712_STATIC | Down | -0.5430238259 |
| GSE19018 | Down | -0.4815133517 |
| GSE19899_A1 | Down | -0.6512609955 |
| GSE19899_A2 | Down | -1.7379025068 |
| PubMed_21979375_A1 | Down | -1.8087017182 |
| PubMed_21979375_A2 | Down | -1.8808426217 |
| GSE35957 | Down | -1.2921412989 |
| GSE36640 | Down | -2.4856831630 |
| GSE54402 | Down | -0.3889105495 |
| GSE9593 | Down | -0.5941057350 |
| GSE43922 | Down | -0.4500823679 |
| GSE24585 | Down | -0.3029836945 |
| GSE37065 | Down | -0.1400337086 |
| GSE28863_A1 | Down | -0.1582491335 |
| GSE28863_A2 | Down | -0.1755016362 |
| GSE28863_A3 | Up | 0.0111549853 |
| GSE28863_A4 | Down | -0.0496231756 |
| GSE48662 | Down | -0.6071651350 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018990 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019470 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031042 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037218 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT046106 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
