HCSGD entry for HLA-DQA1

1. General information

Official gene symbolHLA-DQA1
Entrez ID3117
Gene full namemajor histocompatibility complex, class II, DQ alpha 1
Other gene symbolsCD CELIAC1 DQ-A1 GSE HLA-DQA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0002504Antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEAbiological_process
GO:0005765Lysosomal membraneTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0006955Immune responseIEA NASbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030658Transport vesicle membraneTAScellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0031295T cell costimulationTASbiological_process
GO:0032395MHC class II receptor activityNAS TASmolecular_function
GO:0032588Trans-Golgi network membraneTAScellular_component
GO:0042613MHC class II protein complexIEAcellular_component
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80206449980.21486633490.99999024730.8949073043

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0186758424
GSE13712_SHEARUp0.0104180645
GSE13712_STATICDown-0.0782287061
GSE19018Up0.0711248090
GSE19899_A1Up0.0590770106
GSE19899_A2Up0.1361229919
PubMed_21979375_A1Down-0.1531154935
PubMed_21979375_A2Up0.1240955385
GSE35957Up0.1046696938
GSE36640Up0.0488038979
GSE54402Up0.0078100121
GSE9593Up0.1462657248
GSE43922Up0.0163188309
GSE24585Up0.3705002180
GSE37065Down-0.0757109254
GSE28863_A1Down-1.0121074328
GSE28863_A2Down-1.0883893660
GSE28863_A3Up0.0991054136
GSE28863_A4Up0.0106085990
GSE48662Down-0.0091789866

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-122-5pMIMAT0000421MIRT023357MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.