HCSGD entry for HLA-DPA1

1. General information

Official gene symbolHLA-DPA1
Entrez ID3113
Gene full namemajor histocompatibility complex, class II, DP alpha 1
Other gene symbolsDP(W3) DP(W4) HLA-DP1A HLADP HLASB PLT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0002504Antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIIEAbiological_process
GO:0005765Lysosomal membraneTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0006955Immune responseIEA NASbiological_process
GO:0010008Endosome membraneIEAcellular_component
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0030658Transport vesicle membraneTAScellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0030669Clathrin-coated endocytic vesicle membraneTAScellular_component
GO:0031295T cell costimulationTASbiological_process
GO:0032395MHC class II receptor activityNASmolecular_function
GO:0032588Trans-Golgi network membraneTAScellular_component
GO:0042613MHC class II protein complexIEAcellular_component
GO:0050852T cell receptor signaling pathwayTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0071346Cellular response to interferon-gammaIDAbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05080669810.07137815810.49372177930.5040902871

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0348653653
GSE13712_SHEARDown-0.1158598076
GSE13712_STATICUp0.4526872842
GSE19018Up0.1624928762
GSE19899_A1Up0.1455608801
GSE19899_A2Up0.1795782577
PubMed_21979375_A1Down-0.0959893704
PubMed_21979375_A2Down-0.0103092512
GSE35957Down-1.1630319102
GSE36640Up0.0996253105
GSE54402Up0.1548028668
GSE9593Up0.4536540150
GSE43922Up0.0342609206
GSE24585Up1.1979632778
GSE37065Up0.7620966911
GSE28863_A1Down-0.8228682881
GSE28863_A2Down-0.9159201706
GSE28863_A3Up0.2984815756
GSE28863_A4Down-0.2747802113
GSE48662Down-0.2932751942

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.