HCSGD entry for HLA-B

1. General information

Official gene symbolHLA-B
Entrez ID3106
Gene full namemajor histocompatibility complex, class I, B
Other gene symbolsAS HLAB SPDA1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0001916Positive regulation of T cell mediated cytotoxicityIEAbiological_process
GO:0002474Antigen processing and presentation of peptide antigen via MHC class IIEA TASbiological_process
GO:0002479Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentTASbiological_process
GO:0002480Antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentTASbiological_process
GO:0002667Regulation of T cell anergyIMPbiological_process
GO:0005102Receptor bindingIBA IPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneNAScellular_component
GO:0006952Defense responseTASbiological_process
GO:0006955Immune responseIEA IMP NASbiological_process
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0016045Detection of bacteriumIMPbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0030670Phagocytic vesicle membraneTAScellular_component
GO:0031901Early endosome membraneTAScellular_component
GO:0032655Regulation of interleukin-12 productionIMPbiological_process
GO:0032675Regulation of interleukin-6 productionIMPbiological_process
GO:0042590Antigen processing and presentation of exogenous peptide antigen via MHC class ITASbiological_process
GO:0042605Peptide antigen bindingIBA IEAmolecular_function
GO:0042612MHC class I protein complexIEAcellular_component
GO:0045087Innate immune responseTASbiological_process
GO:0050776Regulation of immune responseTASbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0060337Type I interferon signaling pathwayTASbiological_process
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneTAScellular_component
GO:2001198Regulation of dendritic cell differentiationIMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09633080050.35535366060.64910222221.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0380822047
GSE13712_SHEARUp0.7892472946
GSE13712_STATICUp0.6195287332
GSE19018Up1.0230706181
GSE19899_A1Down-0.6044887996
GSE19899_A2Down-0.0355577722
PubMed_21979375_A1Down-0.6389564602
PubMed_21979375_A2Down-1.4882508270
GSE35957Down-0.3889901839
GSE36640Up1.4647953966
GSE54402Up0.0303028869
GSE9593Down-0.1904978715
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0311180645

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT039965CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.