HCSGD entry for HK3
1. General information
| Official gene symbol | HK3 |
|---|---|
| Entrez ID | 3101 |
| Gene full name | hexokinase 3 (white cell) |
| Other gene symbols | HKIII HXK3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001678 | Cellular glucose homeostasis | IBA | biological_process |
| GO:0004340 | Glucokinase activity | IBA | molecular_function |
| GO:0004396 | Hexokinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | IEA TAS | biological_process |
| GO:0006096 | Glycolysis | IEA | biological_process |
| GO:0008645 | Hexose transport | TAS | biological_process |
| GO:0008865 | Fructokinase activity | IBA | molecular_function |
| GO:0015758 | Glucose transport | TAS | biological_process |
| GO:0016301 | Kinase activity | IEA | molecular_function |
| GO:0016773 | Phosphotransferase activity, alcohol group as acceptor | IEA | molecular_function |
| GO:0019158 | Mannokinase activity | IBA | molecular_function |
| GO:0019899 | Enzyme binding | IEA | molecular_function |
| GO:0042562 | Hormone binding | IEA | molecular_function |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046835 | Carbohydrate phosphorylation | IBA IDA | biological_process |
| GO:0051156 | Glucose 6-phosphate metabolic process | IBA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7209950572 | 0.7997490939 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1102470646 |
| GSE13712_SHEAR | Down | -0.0352638610 |
| GSE13712_STATIC | Down | -0.1119790468 |
| GSE19018 | Down | -0.1737966186 |
| GSE19899_A1 | Up | 0.0419485001 |
| GSE19899_A2 | Down | -0.1165920969 |
| PubMed_21979375_A1 | Down | -0.0256350486 |
| PubMed_21979375_A2 | Up | 0.0630890371 |
| GSE35957 | Up | 0.0210916292 |
| GSE36640 | Down | -0.0714688149 |
| GSE54402 | Up | 0.0024289807 |
| GSE9593 | Up | 0.1213968531 |
| GSE43922 | Up | 0.0608764334 |
| GSE24585 | Up | 0.0142571753 |
| GSE37065 | Down | -0.0757254124 |
| GSE28863_A1 | Down | -0.0740000881 |
| GSE28863_A2 | Up | 0.0361997904 |
| GSE28863_A3 | Up | 0.2122766632 |
| GSE28863_A4 | Up | 0.1668173443 |
| GSE48662 | Up | 0.0361698275 |

