HCSGD entry for HK3


1. General information

Official gene symbolHK3
Entrez ID3101
Gene full namehexokinase 3 (white cell)
Other gene symbolsHKIII HXK3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001678Cellular glucose homeostasisIBAbiological_process
GO:0004340Glucokinase activityIBAmolecular_function
GO:0004396Hexokinase activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005975Carbohydrate metabolic processIEA TASbiological_process
GO:0006096GlycolysisIEAbiological_process
GO:0008645Hexose transportTASbiological_process
GO:0008865Fructokinase activityIBAmolecular_function
GO:0015758Glucose transportTASbiological_process
GO:0016301Kinase activityIEAmolecular_function
GO:0016773Phosphotransferase activity, alcohol group as acceptorIEAmolecular_function
GO:0019158Mannokinase activityIBAmolecular_function
GO:0019899Enzyme bindingIEAmolecular_function
GO:0042562Hormone bindingIEAmolecular_function
GO:0043234Protein complexIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046835Carbohydrate phosphorylationIBA IDAbiological_process
GO:0051156Glucose 6-phosphate metabolic processIBAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72099505720.79974909390.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1102470646
GSE13712_SHEARDown-0.0352638610
GSE13712_STATICDown-0.1119790468
GSE19018Down-0.1737966186
GSE19899_A1Up0.0419485001
GSE19899_A2Down-0.1165920969
PubMed_21979375_A1Down-0.0256350486
PubMed_21979375_A2Up0.0630890371
GSE35957Up0.0210916292
GSE36640Down-0.0714688149
GSE54402Up0.0024289807
GSE9593Up0.1213968531
GSE43922Up0.0608764334
GSE24585Up0.0142571753
GSE37065Down-0.0757254124
GSE28863_A1Down-0.0740000881
GSE28863_A2Up0.0361997904
GSE28863_A3Up0.2122766632
GSE28863_A4Up0.1668173443
GSE48662Up0.0361698275

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.