HCSGD entry for STOML2
1. General information
| Official gene symbol | STOML2 |
|---|---|
| Entrez ID | 30968 |
| Gene full name | stomatin (EPB72)-like 2 |
| Other gene symbols | SLP-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001772 | Immunological synapse | IDA | cellular_component |
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IDA | cellular_component |
| GO:0005758 | Mitochondrial intermembrane space | IDA | cellular_component |
| GO:0005856 | Cytoskeleton | TAS | cellular_component |
| GO:0006851 | Mitochondrial calcium ion transport | IEA IMP | biological_process |
| GO:0006874 | Cellular calcium ion homeostasis | IMP | biological_process |
| GO:0007005 | Mitochondrion organization | IEA IMP | biological_process |
| GO:0008180 | COP9 signalosome | IDA | cellular_component |
| GO:0010876 | Lipid localization | ISS | biological_process |
| GO:0010918 | Positive regulation of mitochondrial membrane potential | IMP | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0019897 | Extrinsic component of plasma membrane | IDA | cellular_component |
| GO:0032623 | Interleukin-2 production | ISS | biological_process |
| GO:0034982 | Mitochondrial protein processing | ISS | biological_process |
| GO:0035710 | CD4-positive, alpha-beta T cell activation | ISS | biological_process |
| GO:0042101 | T cell receptor complex | IDA | cellular_component |
| GO:0042776 | Mitochondrial ATP synthesis coupled proton transport | IEA IMP | biological_process |
| GO:0045121 | Membrane raft | IDA IEA | cellular_component |
| GO:0050852 | T cell receptor signaling pathway | IEA IMP | biological_process |
| GO:0051259 | Protein oligomerization | IDA | biological_process |
| GO:0090297 | Positive regulation of mitochondrial DNA replication | IMP | biological_process |
| GO:1900210 | Positive regulation of cardiolipin metabolic process | IMP | biological_process |
| GO:1901612 | Cardiolipin binding | IDA | molecular_function |
| GO:1990046 | Stress-induced mitochondrial fusion | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8565349379 | 0.0567252954 | 0.9999902473 | 0.4474859707 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0158087504 |
| GSE13712_SHEAR | Down | -0.2463077287 |
| GSE13712_STATIC | Down | -0.1559268813 |
| GSE19018 | Down | -0.4734668669 |
| GSE19899_A1 | Down | -0.1064890157 |
| GSE19899_A2 | Up | 0.0523812117 |
| PubMed_21979375_A1 | Up | 0.8099768016 |
| PubMed_21979375_A2 | Up | 0.0474785824 |
| GSE35957 | Down | -0.7249513902 |
| GSE36640 | Down | -0.9396335464 |
| GSE54402 | Up | 0.5469192169 |
| GSE9593 | Down | -0.4510731673 |
| GSE43922 | Up | 0.0498634216 |
| GSE24585 | Down | -0.3222792906 |
| GSE37065 | Down | -0.1484795519 |
| GSE28863_A1 | Down | -0.0395449445 |
| GSE28863_A2 | Down | -0.4118425634 |
| GSE28863_A3 | Down | -0.2801673625 |
| GSE28863_A4 | Up | 0.1479250449 |
| GSE48662 | Down | -0.1774072978 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029840 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040042 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042553 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044836 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-187-3p | MIMAT0000262 | MIRT047030 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049902 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
