HCSGD entry for EHD4
1. General information
| Official gene symbol | EHD4 |
|---|---|
| Entrez ID | 30844 |
| Gene full name | EH-domain containing 4 |
| Other gene symbols | PAST4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | TAS | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006907 | Pinocytosis | IEA | biological_process |
| GO:0030100 | Regulation of endocytosis | IEA | biological_process |
| GO:0031901 | Early endosome membrane | IEA | cellular_component |
| GO:0032456 | Endocytic recycling | IGI | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0050731 | Positive regulation of peptidyl-tyrosine phosphorylation | IEA | biological_process |
| GO:0051260 | Protein homooligomerization | IPI | biological_process |
| GO:0055038 | Recycling endosome membrane | IDA | cellular_component |
| GO:0071363 | Cellular response to growth factor stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7406590859 | 0.1331085977 | 0.9999902473 | 0.7026777778 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1375244082 |
| GSE13712_SHEAR | Down | -0.1184528642 |
| GSE13712_STATIC | Down | -0.0957351739 |
| GSE19018 | Down | -0.4737872477 |
| GSE19899_A1 | Down | -0.1673400121 |
| GSE19899_A2 | Down | -0.2872864956 |
| PubMed_21979375_A1 | Down | -0.2508306183 |
| PubMed_21979375_A2 | Down | -0.1454300178 |
| GSE35957 | Down | -0.0215391199 |
| GSE36640 | Down | -0.0632872245 |
| GSE54402 | Up | 0.1817468308 |
| GSE9593 | Up | 0.0801588329 |
| GSE43922 | Down | -0.1191622951 |
| GSE24585 | Up | 0.3167466420 |
| GSE37065 | Up | 0.0268980253 |
| GSE28863_A1 | Up | 0.2472333126 |
| GSE28863_A2 | Up | 0.6322834544 |
| GSE28863_A3 | Down | -0.2833190285 |
| GSE28863_A4 | Up | 0.1241820641 |
| GSE48662 | Down | -0.5497143657 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032472 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047751 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
