HCSGD entry for PLA2G2E

1. General information

Official gene symbolPLA2G2E
Entrez ID30814
Gene full namephospholipase A2, group IIE
Other gene symbolsGIIE sPLA2 sPLA2-IIE
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004623Phospholipase A2 activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006654Phosphatidic acid biosynthetic processTASbiological_process
GO:0006954Inflammatory responseTASbiological_process
GO:0016042Lipid catabolic processIEAbiological_process
GO:0036148Phosphatidylglycerol acyl-chain remodelingTASbiological_process
GO:0036149Phosphatidylinositol acyl-chain remodelingTASbiological_process
GO:0036150Phosphatidylserine acyl-chain remodelingTASbiological_process
GO:0036151Phosphatidylcholine acyl-chain remodelingTASbiological_process
GO:0036152Phosphatidylethanolamine acyl-chain remodelingTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046474Glycerophospholipid biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80603440220.63126329550.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0792131496
GSE13712_SHEARUp0.0037578489
GSE13712_STATICUp0.0892051314
GSE19018Up0.0960659475
GSE19899_A1Up0.1880582399
GSE19899_A2Down-0.1307000170
PubMed_21979375_A1Down-0.0402200827
PubMed_21979375_A2Down-0.0416582200
GSE35957Down-0.0429413660
GSE36640Down-0.1003100381
GSE54402Up0.0745557006
GSE9593Down-0.1002496147
GSE43922Up0.0444820509
GSE24585Down-0.0455597817
GSE37065Down-0.2538937010
GSE28863_A1Down-0.1092094718
GSE28863_A2Up0.0506748822
GSE28863_A3Up0.1460031942
GSE28863_A4Up0.0849734572
GSE48662Down-0.0346057486

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Aminosalicylic AcidDB00233 APRD00749 | EXPT00693
1,4-ButanediolDB01955 EXPT00771
N-Tridecanoic AcidDB02448 EXPT03028
9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic AcidDB02636 EXPT00354
Indolylpropionic AcidDB02758 EXPT01908
P-Anisic AcidDB02795 EXPT00523
OxyphenbutazoneDB03585 EXPT02440
GlycerolDB04077 EXPT01027
LicofeloneDB04725 -
NimesulideDB04743 -
2-(4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ETHANAMIDEDB06987 -
(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-oneDB07500 -
1H-INDOL-3-YLACETIC ACIDDB07950 -
(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACIDDB07958 -
3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OLDB08447 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017753MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.