HCSGD entry for HSD17B10
1. General information
| Official gene symbol | HSD17B10 |
|---|---|
| Entrez ID | 3028 |
| Gene full name | hydroxysteroid (17-beta) dehydrogenase 10 |
| Other gene symbols | 17b-HSD10 ABAD CAMR DUPXp11.22 ERAB HADH2 HCD2 MHBD MRPP2 MRX17 MRX31 MRXS10 SCHAD SDR5C1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity | EXP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005739 | Mitochondrion | ISS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006629 | Lipid metabolic process | TAS | biological_process |
| GO:0008033 | TRNA processing | IEA | biological_process |
| GO:0008709 | Cholate 7-alpha-dehydrogenase activity | TAS | molecular_function |
| GO:0009083 | Branched-chain amino acid catabolic process | TAS | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0030283 | Testosterone dehydrogenase [NAD(P)] activity | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047015 | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0918614680 | 0.2208202614 | 0.6376511732 | 0.9046241401 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.7910055898 |
| GSE13712_SHEAR | Down | -0.2060365435 |
| GSE13712_STATIC | Up | 0.2464744561 |
| GSE19018 | Down | -1.0276978349 |
| GSE19899_A1 | Up | 0.2668434969 |
| GSE19899_A2 | Up | 0.6554946902 |
| PubMed_21979375_A1 | Up | 0.7451145607 |
| PubMed_21979375_A2 | Up | 0.4274346103 |
| GSE35957 | Down | -0.5278710230 |
| GSE36640 | Up | 0.2182770214 |
| GSE54402 | Up | 0.6006727949 |
| GSE9593 | Down | -0.3831411782 |
| GSE43922 | Up | 0.3385237092 |
| GSE24585 | Down | -0.1090529648 |
| GSE37065 | Down | -0.2283696154 |
| GSE28863_A1 | Down | -0.1518655965 |
| GSE28863_A2 | Down | -0.2107742604 |
| GSE28863_A3 | Down | -0.1662963216 |
| GSE28863_A4 | Up | 0.1258013160 |
| GSE48662 | Down | -0.7662749264 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
| 1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct | DB02820 | EXPT03033 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022995 | Proteomics;Microarray | Non-Functional MTI (Weak) | 18668037 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025528 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036869 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196b-5p | MIMAT0001080 | MIRT042654 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044743 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048950 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
