HCSGD entry for SLC40A1

1. General information

Official gene symbolSLC40A1
Entrez ID30061
Gene full namesolute carrier family 40 (iron-regulated transporter), member 1
Other gene symbolsFPN1 HFE4 IREG1 MST079 MTP1 SLC11A3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002260Lymphocyte homeostasisIEAbiological_process
GO:0003158Endothelium developmentIEAbiological_process
GO:0005381Iron ion transmembrane transporter activityIEA IMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmTAScellular_component
GO:0005771Multivesicular bodyIEAcellular_component
GO:0005886Plasma membraneIDA IEA TAScellular_component
GO:0005887Integral component of plasma membraneICcellular_component
GO:0006879Cellular iron ion homeostasisIMP TASbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0016021Integral component of membraneIEA TAScellular_component
GO:0034755Iron ion transmembrane transportIMPbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0060345Spleen trabecula formationIEAbiological_process
GO:0060586Multicellular organismal iron ion homeostasisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51225543480.00137173740.99999024730.0715648221

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5055307552
GSE13712_SHEARDown-2.0571034887
GSE13712_STATICDown-0.8922172868
GSE19018Down-0.3521104711
GSE19899_A1Down-0.6605535886
GSE19899_A2Down-2.3575083677
PubMed_21979375_A1Down-0.9975846427
PubMed_21979375_A2Down-0.7197422701
GSE35957Up0.2046716413
GSE36640Down-0.2291704205
GSE54402Down-1.5480233851
GSE9593Up0.9585819216
GSE43922Down-1.8189087911
GSE24585Up0.4722610681
GSE37065Up0.3010278952
GSE28863_A1Down-1.1622108089
GSE28863_A2Up0.4682588480
GSE28863_A3Down-0.0234777417
GSE28863_A4Up0.0535222251
GSE48662Up0.1067818971

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.