HCSGD entry for H1F0
1. General information
| Official gene symbol | H1F0 |
|---|---|
| Entrez ID | 3005 |
| Gene full name | H1 histone family, member 0 |
| Other gene symbols | H10 H1FV |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000786 | Nucleosome | IEA | cellular_component |
| GO:0000790 | Nuclear chromatin | IDA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006309 | Apoptotic DNA fragmentation | TAS | biological_process |
| GO:0006334 | Nucleosome assembly | IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006921 | Cellular component disassembly involved in execution phase of apoptosis | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0251673607 | 0.1774523270 | 0.3728209342 | 0.8147083028 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2127304208 |
| GSE13712_SHEAR | Up | 0.0446247372 |
| GSE13712_STATIC | Down | -0.1060209561 |
| GSE19018 | Up | 1.1023751170 |
| GSE19899_A1 | Up | 0.0577288709 |
| GSE19899_A2 | Down | -0.3552452270 |
| PubMed_21979375_A1 | Down | -0.6512413878 |
| PubMed_21979375_A2 | Down | -0.6775043913 |
| GSE35957 | Down | -0.2036195582 |
| GSE36640 | Down | -1.9161612905 |
| GSE54402 | Down | -0.0910958369 |
| GSE9593 | Up | 0.3531245274 |
| GSE43922 | Down | -0.0385148747 |
| GSE24585 | Up | 2.0881251082 |
| GSE37065 | Up | 0.7751844177 |
| GSE28863_A1 | Up | 0.2785156732 |
| GSE28863_A2 | Up | 0.7419267199 |
| GSE28863_A3 | Up | 0.4057239649 |
| GSE28863_A4 | Down | -0.1216136875 |
| GSE48662 | Up | 0.2771329776 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025115 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040432 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041752 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042482 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045076 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048807 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052457 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 8482357 | H1(0), a less abundant form of H1, may be associated with terminally differentiated or senescent cells |
| 8482357 | In cultures treated to induce higher levels of H1(0) there were no visible differences at the light microscope level in the antibody banding pattern between induced and noninduced cells |
| 8482357 | Highly concentrated regions of H1(0) surround the nucleoli, possibly indicating a cluster of genes that are poised for transcription |
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