HCSGD entry for TLX3
1. General information
| Official gene symbol | TLX3 |
|---|---|
| Entrez ID | 30012 |
| Gene full name | T-cell leukemia homeobox 3 |
| Other gene symbols | HOX11L2 RNX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0002087 | Regulation of respiratory gaseous exchange by neurological system process | IEA | biological_process |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0007417 | Central nervous system development | IEA | biological_process |
| GO:0007585 | Respiratory gaseous exchange | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045665 | Negative regulation of neuron differentiation | IEA | biological_process |
| GO:0048665 | Neuron fate specification | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9094234945 | 0.4854553322 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0767365620 |
| GSE13712_SHEAR | Up | 0.0256193162 |
| GSE13712_STATIC | Down | -0.0816691851 |
| GSE19018 | Down | -0.0542305182 |
| GSE19899_A1 | Down | -0.1323607877 |
| GSE19899_A2 | Up | 0.0447997196 |
| PubMed_21979375_A1 | Down | -0.2797238599 |
| PubMed_21979375_A2 | Down | -0.1182599000 |
| GSE35957 | Up | 0.0747813087 |
| GSE36640 | Up | 0.0226360122 |
| GSE54402 | Down | -0.0800768855 |
| GSE9593 | Down | -0.0023288764 |
| GSE43922 | Down | -0.0102142134 |
| GSE24585 | Down | -0.2089864487 |
| GSE37065 | Down | -0.0308792920 |
| GSE28863_A1 | Down | -0.0143350051 |
| GSE28863_A2 | Down | -0.0208583954 |
| GSE28863_A3 | Up | 0.2396849238 |
| GSE28863_A4 | Up | 0.1624719997 |
| GSE48662 | Down | -0.0174058419 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018007 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029503 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
