HCSGD entry for LMCD1
1. General information
| Official gene symbol | LMCD1 |
|---|---|
| Entrez ID | 29995 |
| Gene full name | LIM and cysteine-rich domains 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003714 | Transcription corepressor activity | IEA ISS | molecular_function |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010611 | Regulation of cardiac muscle hypertrophy | IEA IMP | biological_process |
| GO:0031012 | Extracellular matrix | IDA | cellular_component |
| GO:0070886 | Positive regulation of calcineurin-NFAT signaling cascade | IEA IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4007899282 | 0.0163060750 | 0.9999902473 | 0.2488442899 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.2976626164 |
| GSE13712_SHEAR | Down | -0.8532070713 |
| GSE13712_STATIC | Up | 0.0133403933 |
| GSE19018 | Down | -0.1067829438 |
| GSE19899_A1 | Down | -0.1000206463 |
| GSE19899_A2 | Down | -1.0237314052 |
| PubMed_21979375_A1 | Down | -0.5445089404 |
| PubMed_21979375_A2 | Down | -0.2687833190 |
| GSE35957 | Up | 1.8404020779 |
| GSE36640 | Down | -0.8020160936 |
| GSE54402 | Down | -0.2139058436 |
| GSE9593 | Up | 0.2428530415 |
| GSE43922 | Down | -0.2856496042 |
| GSE24585 | Down | -0.0299952808 |
| GSE37065 | Down | -0.4505668394 |
| GSE28863_A1 | Up | 0.2325386042 |
| GSE28863_A2 | Down | -0.0969611230 |
| GSE28863_A3 | Up | 0.7848758994 |
| GSE28863_A4 | Down | -0.2298797520 |
| GSE48662 | Up | 0.5020314438 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016355 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017807 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029419 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-421 | MIMAT0003339 | MIRT039353 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047240 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
