HCSGD entry for PACSIN1

1. General information

Official gene symbolPACSIN1
Entrez ID29993
Gene full nameprotein kinase C and casein kinase substrate in neurons 1
Other gene symbolsSDPI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005543Phospholipid bindingIDA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIEAcellular_component
GO:0005886Plasma membraneISScellular_component
GO:0007015Actin filament organizationIEAbiological_process
GO:0008092Cytoskeletal protein bindingIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0030137COPI-coated vesicleIEAcellular_component
GO:0030659Cytoplasmic vesicle membraneIEAcellular_component
GO:0032587Ruffle membraneIEA ISScellular_component
GO:0043679Axon terminusISScellular_component
GO:0045202SynapseISScellular_component
GO:0045806Negative regulation of endocytosisIEAbiological_process
GO:0048471Perinuclear region of cytoplasmISScellular_component
GO:0048488Synaptic vesicle endocytosisIEA ISSbiological_process
GO:0048666Neuron developmentIEAbiological_process
GO:0048812Neuron projection morphogenesisISSbiological_process
GO:0072657Protein localization to membraneIEA ISSbiological_process
GO:0090002Establishment of protein localization to plasma membraneISSbiological_process
GO:0097320Membrane tubulationIDA IEAbiological_process
GO:1900006Positive regulation of dendrite developmentISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.64012896170.75977236430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0947720382
GSE13712_SHEARDown-0.1813243107
GSE13712_STATICDown-0.1642420483
GSE19018Down-0.1086633592
GSE19899_A1Down-0.0677437033
GSE19899_A2Up0.0671249389
PubMed_21979375_A1Up0.1259226241
PubMed_21979375_A2Down-0.0443278836
GSE35957Up0.1247117139
GSE36640Up0.0524360593
GSE54402Up0.0184426402
GSE9593Up0.0538198405
GSE43922Up0.1448410493
GSE24585Up0.0741504133
GSE37065Down-0.0850413895
GSE28863_A1Down-0.2141563444
GSE28863_A2Down-0.0861139506
GSE28863_A3Up0.2896981795
GSE28863_A4Up0.2314748051
GSE48662Up0.0074978974

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.