HCSGD entry for UBQLN1
1. General information
| Official gene symbol | UBQLN1 |
|---|---|
| Entrez ID | 29979 |
| Gene full name | ubiquilin 1 |
| Other gene symbols | DA41 DSK2 PLIC-1 UBQN XDRP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000502 | Proteasome complex | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IMP | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0019900 | Kinase binding | IPI | molecular_function |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0031396 | Regulation of protein ubiquitination | IDA | biological_process |
| GO:0034976 | Response to endoplasmic reticulum stress | IMP | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IDA NAS | cellular_component |
| GO:0071456 | Cellular response to hypoxia | IMP | biological_process |
| GO:0097194 | Execution phase of apoptosis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6917679154 | 0.5807574332 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1857173791 |
| GSE13712_SHEAR | Down | -0.0256073178 |
| GSE13712_STATIC | Down | -0.0384835873 |
| GSE19018 | Down | -0.2350085631 |
| GSE19899_A1 | Up | 0.0420519385 |
| GSE19899_A2 | Up | 0.2927783160 |
| PubMed_21979375_A1 | Up | 0.2640363717 |
| PubMed_21979375_A2 | Up | 0.1469866879 |
| GSE35957 | Down | -0.1749810838 |
| GSE36640 | Down | -0.0338690540 |
| GSE54402 | Up | 0.1881592580 |
| GSE9593 | Up | 0.0755924097 |
| GSE43922 | Up | 0.0020269962 |
| GSE24585 | Down | -0.0621711281 |
| GSE37065 | Up | 0.0858383763 |
| GSE28863_A1 | Down | -0.1784157403 |
| GSE28863_A2 | Down | -0.0499090812 |
| GSE28863_A3 | Down | -0.5329305066 |
| GSE28863_A4 | Up | 0.2300963957 |
| GSE48662 | Down | -0.2925627516 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT003156 | immunoprecipitaion//Microarray//qRT-PCR | Functional MTI (Weak) | 19826008 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020996 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020996 | Reporter assay;Other | Functional MTI | 20584899 |
| hsa-miR-484 | MIMAT0002174 | MIRT042191 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043312 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048505 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
