HCSGD entry for GYS1
1. General information
| Official gene symbol | GYS1 |
|---|---|
| Entrez ID | 2997 |
| Gene full name | glycogen synthase 1 (muscle) |
| Other gene symbols | GSY GYS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004373 | Glycogen (starch) synthase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005536 | Glucose binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0005978 | Glycogen biosynthetic process | IDA IEA TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0007507 | Heart development | IEA | biological_process |
| GO:0016234 | Inclusion body | IEA | cellular_component |
| GO:0019901 | Protein kinase binding | IPI | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0302124311 | 0.0249316857 | 0.4028477204 | 0.3046550139 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.6059216795 |
| GSE13712_SHEAR | Down | -0.1073403398 |
| GSE13712_STATIC | Up | 0.3073829034 |
| GSE19018 | Up | 1.2012564270 |
| GSE19899_A1 | Down | -1.3445214772 |
| GSE19899_A2 | Up | 0.6382683157 |
| PubMed_21979375_A1 | Up | 0.4611105662 |
| PubMed_21979375_A2 | Up | 1.9687923009 |
| GSE35957 | Down | -0.7931355234 |
| GSE36640 | Up | 0.1880497737 |
| GSE54402 | Up | 0.7710133886 |
| GSE9593 | Down | -0.3604675355 |
| GSE43922 | Down | -0.1421760322 |
| GSE24585 | Down | -0.6014527805 |
| GSE37065 | Down | -0.2400236832 |
| GSE28863_A1 | Up | 0.1194660824 |
| GSE28863_A2 | Up | 0.4027110226 |
| GSE28863_A3 | Down | -0.4811716136 |
| GSE28863_A4 | Down | -0.2214017434 |
| GSE48662 | Up | 0.3672457851 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001626 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT003080 | qRT-PCR//Western blot//Northern blot | Functional MTI | 18073344 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT003080 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028992 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
