HCSGD entry for MDFIC


1. General information

Official gene symbolMDFIC
Entrez ID29969
Gene full nameMyoD family inhibitor domain containing
Other gene symbolsHIC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDA IEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007257Activation of JUN kinase activityIDAbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0016032Viral processIEAbiological_process
GO:0030111Regulation of Wnt signaling pathwayIDAbiological_process
GO:0030332Cyclin bindingIPImolecular_function
GO:0030957Tat protein bindingIDAmolecular_function
GO:0042308Negative regulation of protein import into nucleusIEA ISSbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIEA ISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0050434Positive regulation of viral transcriptionIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62773520000.17937522890.99999024730.8203742059

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0284412289
GSE13712_SHEARDown-0.5041279648
GSE13712_STATICDown-0.3314129998
GSE19018Down-0.1687114543
GSE19899_A1Up0.2706107652
GSE19899_A2Up0.1221473998
PubMed_21979375_A1Up0.7991154461
PubMed_21979375_A2Down-0.2218387664
GSE35957Up0.0927733458
GSE36640Down-0.8137509099
GSE54402Up0.6560757531
GSE9593Down-0.5056476642
GSE43922Down-0.0142520578
GSE24585Up0.1468454061
GSE37065Down-0.0067275958
GSE28863_A1Down-0.0542110566
GSE28863_A2Up0.1826180031
GSE28863_A3Down-0.4260582849
GSE28863_A4Down-0.0864632899
GSE48662Down-0.0642278376

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT002667MicroarrayFunctional MTI (Weak)15685193
hsa-miR-132-3pMIMAT0000426MIRT021846MicroarrayFunctional MTI (Weak)17612493
hsa-miR-221-3pMIMAT0000278MIRT046893CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.