HCSGD entry for LRP12
1. General information
| Official gene symbol | LRP12 |
|---|---|
| Entrez ID | 29967 |
| Gene full name | low density lipoprotein receptor-related protein 12 |
| Other gene symbols | ST7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005041 | Low-density lipoprotein receptor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0005905 | Coated pit | IEA | cellular_component |
| GO:0006897 | Endocytosis | NAS | biological_process |
| GO:0006898 | Receptor-mediated endocytosis | NAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0040008 | Regulation of growth | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0261899928 | 0.5662885415 | 0.3783462130 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7881118474 |
| GSE13712_SHEAR | Up | 0.8239887088 |
| GSE13712_STATIC | Up | 0.7896435156 |
| GSE19018 | Up | 0.2678893555 |
| GSE19899_A1 | Down | -0.1010029346 |
| GSE19899_A2 | Up | 0.0663472055 |
| PubMed_21979375_A1 | Up | 0.2342400565 |
| PubMed_21979375_A2 | Down | -0.1639966311 |
| GSE35957 | Up | 0.7051276006 |
| GSE36640 | Up | 1.0319800019 |
| GSE54402 | Up | 0.2349686470 |
| GSE9593 | Up | 0.7278780866 |
| GSE43922 | Up | 0.1852094022 |
| GSE24585 | Up | 0.0131091252 |
| GSE37065 | Up | 0.1644237636 |
| GSE28863_A1 | Down | -0.2060068931 |
| GSE28863_A2 | Up | 0.2827228658 |
| GSE28863_A3 | Down | -1.0318971452 |
| GSE28863_A4 | Up | 0.1297309610 |
| GSE48662 | Up | 0.3266098923 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040084 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 10491433 | 2-specific YAC clone, located in the vicinity of the fragile histidine triad (FHIT) gene (but toward the telomere), that is capable of inducing sustained suppression of tumorigenicity in nude mice and of activating cellular senescence in vitro |
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