HCSGD entry for TRHDE
1. General information
| Official gene symbol | TRHDE |
|---|---|
| Entrez ID | 29953 |
| Gene full name | thyrotropin-releasing hormone degrading enzyme |
| Other gene symbols | PAP-II PGPEP2 TRH-DE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004177 | Aminopeptidase activity | IEA | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0008237 | Metallopeptidase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9021709737 | 0.0014076745 | 0.9999902473 | 0.0725291585 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1218459544 |
| GSE13712_SHEAR | Down | -0.1145691902 |
| GSE13712_STATIC | Up | 0.1552755517 |
| GSE19018 | Up | 1.7145277308 |
| GSE19899_A1 | Down | -0.9962028269 |
| GSE19899_A2 | Down | -0.8868960177 |
| PubMed_21979375_A1 | Down | -3.1600655660 |
| PubMed_21979375_A2 | Down | -1.2148914406 |
| GSE35957 | Up | 0.2397591076 |
| GSE36640 | Down | -0.7689699703 |
| GSE54402 | Down | -0.8063555555 |
| GSE9593 | Down | -0.2657380005 |
| GSE43922 | Down | -0.8135488152 |
| GSE24585 | Down | -0.1326398789 |
| GSE37065 | Down | -0.0135700075 |
| GSE28863_A1 | Down | -0.3067741353 |
| GSE28863_A2 | Down | -0.6055020094 |
| GSE28863_A3 | Down | -0.5763969458 |
| GSE28863_A4 | Down | -0.2335362542 |
| GSE48662 | Up | 0.0471915256 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
