HCSGD entry for DPP7
1. General information
| Official gene symbol | DPP7 |
|---|---|
| Entrez ID | 29952 |
| Gene full name | dipeptidyl-peptidase 7 |
| Other gene symbols | DPP2 DPPII QPP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004177 | Aminopeptidase activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008236 | Serine-type peptidase activity | IEA | molecular_function |
| GO:0008239 | Dipeptidyl-peptidase activity | IEA | molecular_function |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0918316591 | 0.9427361612 | 0.6376511732 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2534220576 |
| GSE13712_SHEAR | Down | -0.2557994331 |
| GSE13712_STATIC | Down | -0.2220626876 |
| GSE19018 | Up | 0.0267397864 |
| GSE19899_A1 | Down | -0.0940102738 |
| GSE19899_A2 | Up | 0.7103976986 |
| PubMed_21979375_A1 | Up | 0.3392770857 |
| PubMed_21979375_A2 | Up | 1.1362777682 |
| GSE35957 | Up | 0.0166968652 |
| GSE36640 | Up | 0.3851800524 |
| GSE54402 | Up | 0.1298349390 |
| GSE9593 | Up | 0.1383967225 |
| GSE43922 | Down | -0.1463641924 |
| GSE24585 | Up | 0.1911399702 |
| GSE37065 | Up | 0.0710871374 |
| GSE28863_A1 | Down | -0.0660854581 |
| GSE28863_A2 | Down | -0.0189558418 |
| GSE28863_A3 | Up | 0.1848848749 |
| GSE28863_A4 | Up | 0.0685116329 |
| GSE48662 | Up | 0.7791865037 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001551 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023714 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 7020767 | The calculated half-lives were: 60 days for the neutral endopeptidase; 87 days for the total acidic endopeptidase activity which is accounted for by three distinct enzymes; 49 days for aminopeptidase B and 133 days for a second aminopeptidase with broad substrate specificity; 84 days for dipeptidyl aminopeptidase II |
| 7020767 | The results obtained with the rabbit erythrocytes were: (a) no significant decline of leucine aminopeptidase, dipeptidyl aminopeptidase II and III activities in the transition from reticulocytes to mature erythrocytes; (b) very limited decline of aminopeptidase B activity; (c) a pronounced age-dependent decay, in increasing order, of neutral endopeptidase, aminopeptidase A, carboxypeptidase and acidic endopeptidase activities |
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