HCSGD entry for PKN3
1. General information
| Official gene symbol | PKN3 |
|---|---|
| Entrez ID | 29941 |
| Gene full name | protein kinase N3 |
| Other gene symbols | RP11-545E17.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | TAS | molecular_function |
| GO:0004697 | Protein kinase C activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | TAS | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0010631 | Epithelial cell migration | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9254307397 | 0.0579807264 | 0.9999902473 | 0.4529153116 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0446862772 |
| GSE13712_SHEAR | Down | -0.3474461007 |
| GSE13712_STATIC | Down | -0.2606467881 |
| GSE19018 | Up | 0.1505673172 |
| GSE19899_A1 | Down | -0.1834646020 |
| GSE19899_A2 | Down | -0.6436271637 |
| PubMed_21979375_A1 | Down | -0.3461370407 |
| PubMed_21979375_A2 | Down | -0.5190142433 |
| GSE35957 | Down | -0.8479463992 |
| GSE36640 | Down | -1.0712354721 |
| GSE54402 | Down | -0.2059977565 |
| GSE9593 | Up | 0.0393675016 |
| GSE43922 | Up | 0.1501614986 |
| GSE24585 | Up | 0.0226642648 |
| GSE37065 | Down | -0.0440517193 |
| GSE28863_A1 | Down | -0.0654249210 |
| GSE28863_A2 | Up | 0.1296747187 |
| GSE28863_A3 | Up | 0.1246516535 |
| GSE28863_A4 | Up | 0.1058977461 |
| GSE48662 | Down | -0.6030742986 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016540 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036498 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039934 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042972 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
