HCSGD entry for EEF2K
1. General information
| Official gene symbol | EEF2K |
|---|---|
| Entrez ID | 29904 |
| Gene full name | eukaryotic elongation factor-2 kinase |
| Other gene symbols | HSU93850 eEF-2K |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004686 | Elongation factor-2 kinase activity | IDA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005516 | Calmodulin binding | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006414 | Translational elongation | TAS | biological_process |
| GO:0008135 | Translation factor activity, nucleic acid binding | TAS | molecular_function |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0031952 | Regulation of protein autophosphorylation | IEA | biological_process |
| GO:0046777 | Protein autophosphorylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0653167585 | 0.9962388017 | 0.5508498558 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.6745222518 |
| GSE28863_A2 | Up | 0.4060172719 |
| GSE28863_A3 | Down | -0.0120540839 |
| GSE28863_A4 | Down | -0.0023982860 |
| GSE48662 | Up | 0.3352653835 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-9-5p | MIMAT0000441 | MIRT021460 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036987 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051093 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
