HCSGD entry for GUSB
1. General information
| Official gene symbol | GUSB |
|---|---|
| Entrez ID | 2990 |
| Gene full name | glucuronidase, beta |
| Other gene symbols | BG MPS7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004553 | Hydrolase activity, hydrolyzing O-glycosyl compounds | IEA | molecular_function |
| GO:0004566 | Beta-glucuronidase activity | TAS | molecular_function |
| GO:0005975 | Carbohydrate metabolic process | IEA TAS | biological_process |
| GO:0006027 | Glycosaminoglycan catabolic process | TAS | biological_process |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0030212 | Hyaluronan metabolic process | TAS | biological_process |
| GO:0030214 | Hyaluronan catabolic process | TAS | biological_process |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9751943733 | 0.0107902321 | 0.9999902473 | 0.2058041304 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5561678542 |
| GSE13712_SHEAR | Down | -0.0127634001 |
| GSE13712_STATIC | Down | -0.2129791334 |
| GSE19018 | Up | 0.0866445035 |
| GSE19899_A1 | Down | -0.7083564903 |
| GSE19899_A2 | Down | -0.4472553834 |
| PubMed_21979375_A1 | Down | -0.7463395056 |
| PubMed_21979375_A2 | Down | -0.6211473316 |
| GSE35957 | Down | -0.4981949731 |
| GSE36640 | Down | -0.9070433322 |
| GSE54402 | Down | -0.6522797523 |
| GSE9593 | Down | -0.5207517419 |
| GSE43922 | Down | -0.4995241595 |
| GSE24585 | Up | 0.2071188539 |
| GSE37065 | Down | -0.2668925770 |
| GSE28863_A1 | Up | 0.3663101012 |
| GSE28863_A2 | Up | 0.4860350378 |
| GSE28863_A3 | Down | -0.0943679457 |
| GSE28863_A4 | Down | -0.1149398975 |
| GSE48662 | Up | 0.0500892865 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030165 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-760 | MIMAT0004957 | MIRT036746 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
