HCSGD entry for CPSF1
1. General information
| Official gene symbol | CPSF1 |
|---|---|
| Entrez ID | 29894 |
| Gene full name | cleavage and polyadenylation specific factor 1, 160kDa |
| Other gene symbols | CPSF160 HSU37012 P/cl.18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003730 | MRNA 3'-UTR binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005847 | MRNA cleavage and polyadenylation specificity factor complex | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006378 | MRNA polyadenylation | IDA | biological_process |
| GO:0006379 | MRNA cleavage | IDA | biological_process |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4539468713 | 0.4224990312 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1354249420 |
| GSE13712_SHEAR | Up | 0.1984242628 |
| GSE13712_STATIC | Up | 0.3067864379 |
| GSE19018 | Down | -0.1302559397 |
| GSE19899_A1 | Up | 0.0123623440 |
| GSE19899_A2 | Up | 0.1549293420 |
| PubMed_21979375_A1 | Down | -0.4660959724 |
| PubMed_21979375_A2 | Down | -0.0794765954 |
| GSE35957 | Up | 0.1475700748 |
| GSE36640 | Down | -0.1125136797 |
| GSE54402 | Up | 0.0606659089 |
| GSE9593 | Up | 0.2386284986 |
| GSE43922 | Up | 0.0380755687 |
| GSE24585 | Down | -0.1088686903 |
| GSE37065 | Down | -0.2742824603 |
| GSE28863_A1 | Up | 0.0888223264 |
| GSE28863_A2 | Up | 0.0589739717 |
| GSE28863_A3 | Up | 0.2850021354 |
| GSE28863_A4 | Up | 0.1284373803 |
| GSE48662 | Down | -0.3631087562 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT004179 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-1 | MIMAT0000416 | MIRT023819 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028569 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032424 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT051016 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
