HCSGD entry for GUCY1A3

1. General information

Official gene symbolGUCY1A3
Entrez ID2982
Gene full nameguanylate cyclase 1, soluble, alpha 3
Other gene symbolsGC-SA3 GUC1A3 GUCA3 GUCSA3 GUCY1A1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0004383Guanylate cyclase activityIEAmolecular_function
GO:0004872Receptor activityTASmolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0007263Nitric oxide mediated signal transductionTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008015Blood circulationTASbiological_process
GO:0008074Guanylate cyclase complex, solubleTAScellular_component
GO:0008217Regulation of blood pressureIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0020037Heme bindingIEAmolecular_function
GO:0030828Positive regulation of cGMP biosynthetic processIEAbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0052565Response to defense-related host nitric oxide productionIEAbiological_process
GO:0060087Relaxation of vascular smooth muscleIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90145513470.19369273580.99999024730.8531013385

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0798064110
GSE13712_SHEARDown-0.6447111623
GSE13712_STATICDown-0.2589521281
GSE19018Down-0.2205429296
GSE19899_A1Down-0.0013684448
GSE19899_A2Up0.0239388393
PubMed_21979375_A1Up0.0464909735
PubMed_21979375_A2Down-0.0519593436
GSE35957Up0.1558676834
GSE36640Up0.0283739979
GSE54402Down-0.0326124622
GSE9593Down-0.0085486694
GSE43922Up0.0135543425
GSE24585Down-1.1120308578
GSE37065Up0.0055595448
GSE28863_A1Up0.0393880915
GSE28863_A2Down-0.0924409552
GSE28863_A3Up0.1559959792
GSE28863_A4Up0.0572781966
GSE48662Up0.0420091469

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.