HCSGD entry for GUCA1B


1. General information

Official gene symbolGUCA1B
Entrez ID2979
Gene full nameguanylate cyclase activator 1B (retina)
Other gene symbolsGCAP2 GUCA2 RP48
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001917Photoreceptor inner segmentIEAcellular_component
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0007168Receptor guanylyl cyclase signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007589Body fluid secretionTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0008048Calcium sensitive guanylate cyclase activator activityIEAmolecular_function
GO:0016056Rhodopsin mediated signaling pathwayTASbiological_process
GO:0022400Regulation of rhodopsin mediated signaling pathwayTASbiological_process
GO:0031284Positive regulation of guanylate cyclase activityTASbiological_process
GO:0043085Positive regulation of catalytic activityTASbiological_process
GO:0097381Photoreceptor disc membraneTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.48051110140.92165234980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0759081761
GSE13712_SHEARDown-0.0220148864
GSE13712_STATICDown-0.0448014150
GSE19018Down-0.0127904036
GSE19899_A1Up0.0750768855
GSE19899_A2Up0.0040628230
PubMed_21979375_A1Down-0.2518893390
PubMed_21979375_A2Up0.0545217483
GSE35957Up0.1497357198
GSE36640Up0.4714147772
GSE54402Up0.0062719868
GSE9593Up0.0653534942
GSE43922Up0.0139498830
GSE24585Up0.0194812686
GSE37065Up0.0304993275
GSE28863_A1Up0.0585039533
GSE28863_A2Up0.2150730469
GSE28863_A3Up0.0553604213
GSE28863_A4Up0.1581915373
GSE48662Up0.0076190459

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.