HCSGD entry for ABT1
1. General information
| Official gene symbol | ABT1 |
|---|---|
| Entrez ID | 29777 |
| Gene full name | activator of basal transcription 1 |
| Other gene symbols | hABT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0021522 | Spinal cord motor neuron differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3469879868 | 0.5184966681 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1472189454 |
| GSE13712_SHEAR | Down | -0.1458743209 |
| GSE13712_STATIC | Up | 0.1931040109 |
| GSE19018 | Down | -0.3636626909 |
| GSE19899_A1 | Up | 0.2077374418 |
| GSE19899_A2 | Up | 0.4766916191 |
| PubMed_21979375_A1 | Up | 0.8094443587 |
| PubMed_21979375_A2 | Up | 0.3251519055 |
| GSE35957 | Down | -0.1331516541 |
| GSE36640 | Down | -0.2638177801 |
| GSE54402 | Up | 0.3168335239 |
| GSE9593 | Down | -0.2951490261 |
| GSE43922 | Up | 0.0918985396 |
| GSE24585 | Down | -0.1177944027 |
| GSE37065 | Up | 0.0110340550 |
| GSE28863_A1 | Down | -0.1342999771 |
| GSE28863_A2 | Down | -0.0340755471 |
| GSE28863_A3 | Down | -0.3407416741 |
| GSE28863_A4 | Down | -0.0843633582 |
| GSE48662 | Down | -0.0372341236 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023111 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026032 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027859 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032165 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039696 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041584 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043755 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044910 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
