HCSGD entry for USP25
1. General information
| Official gene symbol | USP25 |
|---|---|
| Entrez ID | 29761 |
| Gene full name | ubiquitin specific peptidase 25 |
| Other gene symbols | USP21 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004221 | Ubiquitin thiolesterase activity | IEA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006508 | Proteolysis | TAS | biological_process |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0008233 | Peptidase activity | TAS | molecular_function |
| GO:0032183 | SUMO binding | IDA | molecular_function |
| GO:0070536 | Protein K63-linked deubiquitination | IMP | biological_process |
| GO:0071108 | Protein K48-linked deubiquitination | IMP | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0618277231 | 0.9471871130 | 0.5388634106 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1964477396 |
| GSE13712_SHEAR | Up | 0.3180926199 |
| GSE13712_STATIC | Up | 0.1096840469 |
| GSE19018 | Up | 0.0453957280 |
| GSE19899_A1 | Up | 0.3167693066 |
| GSE19899_A2 | Up | 0.3194337126 |
| PubMed_21979375_A1 | Up | 0.7943969995 |
| PubMed_21979375_A2 | Down | -0.0275979939 |
| GSE35957 | Up | 0.0732357801 |
| GSE36640 | Down | -0.1910380473 |
| GSE54402 | Up | 0.2546686817 |
| GSE9593 | Up | 0.0907339769 |
| GSE43922 | Up | 0.1518560852 |
| GSE24585 | Up | 0.2071779906 |
| GSE37065 | Up | 0.0820920267 |
| GSE28863_A1 | Up | 0.6567499646 |
| GSE28863_A2 | Up | 0.3029110055 |
| GSE28863_A3 | Down | -0.1858610625 |
| GSE28863_A4 | Up | 0.1902977847 |
| GSE48662 | Down | -0.2444826143 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT022093 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027319 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028715 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-454-5p | MIMAT0003884 | MIRT039252 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
