HCSGD entry for BLNK
1. General information
| Official gene symbol | BLNK |
|---|---|
| Entrez ID | 29760 |
| Gene full name | B-cell linker |
| Other gene symbols | AGM4 BASH BLNK-S LY57 SLP-65 SLP65 bca |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005068 | Transmembrane receptor protein tyrosine kinase adaptor activity | TAS | molecular_function |
| GO:0005070 | SH3/SH2 adaptor activity | IDA RCA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | NAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006954 | Inflammatory response | TAS | biological_process |
| GO:0006959 | Humoral immune response | TAS | biological_process |
| GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | TAS | biological_process |
| GO:0009967 | Positive regulation of signal transduction | IDA RCA | biological_process |
| GO:0030183 | B cell differentiation | NAS | biological_process |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2807951066 | 0.4984463318 | 0.9782851264 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0908249523 |
| GSE13712_SHEAR | Down | -0.3777684265 |
| GSE13712_STATIC | Down | -0.1403666659 |
| GSE19018 | Up | 0.1269773411 |
| GSE19899_A1 | Up | 0.1107864198 |
| GSE19899_A2 | Up | 0.1656382898 |
| PubMed_21979375_A1 | Up | 0.1949573660 |
| PubMed_21979375_A2 | Up | 0.2389987169 |
| GSE35957 | Up | 0.1823794309 |
| GSE36640 | Down | -0.0762669884 |
| GSE54402 | Up | 0.0102137642 |
| GSE9593 | Up | 0.4926775341 |
| GSE43922 | Up | 0.0337240469 |
| GSE24585 | Up | 0.5881426155 |
| GSE37065 | Up | 0.3852201598 |
| GSE28863_A1 | Down | -0.5298055178 |
| GSE28863_A2 | Down | -0.6195215602 |
| GSE28863_A3 | Up | 0.1758424085 |
| GSE28863_A4 | Down | -0.0101730567 |
| GSE48662 | Up | 0.1788234069 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029539 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
