HCSGD entry for GTF3C2
1. General information
| Official gene symbol | GTF3C2 |
|---|---|
| Entrez ID | 2976 |
| Gene full name | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| Other gene symbols | TFIIIC-BETA TFIIIC110 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000127 | Transcription factor TFIIIC complex | IDA | cellular_component |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IDA | biological_process |
| GO:0006383 | Transcription from RNA polymerase III promoter | IDA TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0042791 | 5S class rRNA transcription from RNA polymerase III type 1 promoter | IC | biological_process |
| GO:0042797 | TRNA transcription from RNA polymerase III promoter | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2937591087 | 0.3596095057 | 0.9939623988 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3400837010 |
| GSE13712_SHEAR | Down | -0.2720840742 |
| GSE13712_STATIC | Down | -0.1931234919 |
| GSE19018 | Down | -0.2288374727 |
| GSE19899_A1 | Down | -0.0055037166 |
| GSE19899_A2 | Up | 0.3673809214 |
| PubMed_21979375_A1 | Up | 0.4013152853 |
| PubMed_21979375_A2 | Up | 0.7851427329 |
| GSE35957 | Up | 0.0138979620 |
| GSE36640 | Down | -0.4073717463 |
| GSE54402 | Up | 0.2791802610 |
| GSE9593 | Up | 0.2568665208 |
| GSE43922 | Up | 0.3310028395 |
| GSE24585 | Down | -0.3562238640 |
| GSE37065 | Down | -0.1737347651 |
| GSE28863_A1 | Down | -0.0347043302 |
| GSE28863_A2 | Up | 0.3646837073 |
| GSE28863_A3 | Down | -0.2605011191 |
| GSE28863_A4 | Down | -0.2273006633 |
| GSE48662 | Down | -0.3865938352 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030484 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031765 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047625 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049553 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
