HCSGD entry for GTF2F1

1. General information

Official gene symbolGTF2F1
Entrez ID2962
Gene full namegeneral transcription factor IIF, polypeptide 1, 74kDa
Other gene symbolsBTF4 RAP74 TF2F1 TFIIF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003713Transcription coactivator activityTASmolecular_function
GO:0003824Catalytic activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005674Transcription factor TFIIF complexTAScellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterIEA TASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0008380RNA splicingTASbiological_process
GO:0009615Response to virusIEPbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0019211Phosphatase activator activityIDAmolecular_function
GO:0030054Cell junctionIDAcellular_component
GO:0043085Positive regulation of catalytic activityIDAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
GO:0050790Regulation of catalytic activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04211612780.76566641840.45864236661.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5168998823
GSE13712_SHEARDown-0.2067275370
GSE13712_STATICUp0.0544556429
GSE19018Down-0.1012812612
GSE19899_A1Down-0.0051312070
GSE19899_A2Up0.6180842832
PubMed_21979375_A1Up1.0567918547
PubMed_21979375_A2Up0.4419826983
GSE35957Down-0.7202224429
GSE36640Down-0.0863463201
GSE54402Up0.3653410272
GSE9593Up0.2253114149
GSE43922Up0.1352976809
GSE24585Up0.1839456061
GSE37065Down-0.1511064205
GSE28863_A1Down-0.1828178841
GSE28863_A2Down-0.4958190036
GSE28863_A3Up0.7041355898
GSE28863_A4Up0.1511446543
GSE48662Up0.1900757604

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-423-5pMIMAT0004748MIRT038149CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.