HCSGD entry for GTF2E1
1. General information
| Official gene symbol | GTF2E1 |
|---|---|
| Entrez ID | 2960 |
| Gene full name | general transcription factor IIE, polypeptide 1, alpha 56kDa |
| Other gene symbols | FE TF2E1 TFIIE-A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2234267733 | 0.4304905361 | 0.9040289793 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4989709029 |
| GSE13712_SHEAR | Down | -0.0229189994 |
| GSE13712_STATIC | Up | 0.1168150125 |
| GSE19018 | Down | -0.4934747540 |
| GSE19899_A1 | Up | 0.2694402574 |
| GSE19899_A2 | Up | 0.1332503112 |
| PubMed_21979375_A1 | Up | 0.5194706462 |
| PubMed_21979375_A2 | Up | 0.4523698673 |
| GSE35957 | Down | -0.4877350269 |
| GSE36640 | Up | 0.1250768020 |
| GSE54402 | Up | 0.2453855241 |
| GSE9593 | Down | -0.1845197813 |
| GSE43922 | Up | 0.3203213980 |
| GSE24585 | Up | 0.0286605048 |
| GSE37065 | Up | 0.2046003245 |
| GSE28863_A1 | Down | -0.3042181000 |
| GSE28863_A2 | Up | 0.0011138191 |
| GSE28863_A3 | Down | -0.5395759149 |
| GSE28863_A4 | Down | -0.0832831749 |
| GSE48662 | Down | -0.1746466843 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-361-5p | MIMAT0000703 | MIRT020098 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024145 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030375 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051392 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
