HCSGD entry for GTF2A2
1. General information
| Official gene symbol | GTF2A2 |
|---|---|
| Entrez ID | 2958 |
| Gene full name | general transcription factor IIA, 2, 12kDa |
| Other gene symbols | HsT18745 TF2A2 TFIIA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001103 | RNA polymerase II repressing transcription factor binding | IEA | molecular_function |
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005672 | Transcription factor TFIIA complex | IDA IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | IDA TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | IEA TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0017025 | TBP-class protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0051091 | Positive regulation of sequence-specific DNA binding transcription factor activity | IDA | biological_process |
| GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8832924737 | 0.2305214468 | 0.9999902473 | 0.9247795309 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1609395770 |
| GSE13712_SHEAR | Up | 0.3993242482 |
| GSE13712_STATIC | Down | -0.1119011922 |
| GSE19018 | Down | -0.2719784810 |
| GSE19899_A1 | Down | -0.0169475363 |
| GSE19899_A2 | Down | -0.1722270844 |
| PubMed_21979375_A1 | Down | -0.3872761882 |
| PubMed_21979375_A2 | Down | -0.1229787969 |
| GSE35957 | Down | -0.3159477480 |
| GSE36640 | Up | 0.1816809010 |
| GSE54402 | Up | 0.0198905757 |
| GSE9593 | Down | -0.2135071538 |
| GSE43922 | Up | 0.0027711521 |
| GSE24585 | Up | 0.0300262185 |
| GSE37065 | Up | 0.0471752107 |
| GSE28863_A1 | Down | -0.1820627463 |
| GSE28863_A2 | Down | -0.2097699228 |
| GSE28863_A3 | Down | -0.1409276383 |
| GSE28863_A4 | Up | 0.0355378332 |
| GSE48662 | Down | -0.0396181045 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029382 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
