HCSGD entry for GSTZ1
1. General information
| Official gene symbol | GSTZ1 |
|---|---|
| Entrez ID | 2954 |
| Gene full name | glutathione S-transferase zeta 1 |
| Other gene symbols | GSTZ1-1 MAAI MAI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004364 | Glutathione transferase activity | IDA | molecular_function |
| GO:0004602 | Glutathione peroxidase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA ISS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006559 | L-phenylalanine catabolic process | IEA TAS | biological_process |
| GO:0006572 | Tyrosine catabolic process | IEA | biological_process |
| GO:0006749 | Glutathione metabolic process | IDA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0009072 | Aromatic amino acid family metabolic process | IEA | biological_process |
| GO:0016034 | Maleylacetoacetate isomerase activity | EXP IDA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055114 | Oxidation-reduction process | TAS | biological_process |
| GO:1901687 | Glutathione derivative biosynthetic process | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5480550435 | 0.3108661107 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0168716907 |
| GSE13712_SHEAR | Up | 0.1718186631 |
| GSE13712_STATIC | Up | 0.4106855926 |
| GSE19018 | Down | -0.0826346165 |
| GSE19899_A1 | Down | -0.0481137643 |
| GSE19899_A2 | Down | -0.2211143005 |
| PubMed_21979375_A1 | Down | -0.1527121568 |
| PubMed_21979375_A2 | Down | -0.0158040309 |
| GSE35957 | Down | -0.4631434150 |
| GSE36640 | Down | -0.0557029412 |
| GSE54402 | Down | -0.0072563654 |
| GSE9593 | Down | -0.4419930871 |
| GSE43922 | Down | -0.0051567158 |
| GSE24585 | Up | 0.0589403949 |
| GSE37065 | Up | 0.0310929688 |
| GSE28863_A1 | Down | -0.1264362043 |
| GSE28863_A2 | Down | -0.3209030070 |
| GSE28863_A3 | Up | 0.3790002412 |
| GSE28863_A4 | Up | 0.0718740511 |
| GSE48662 | Up | 0.2264686938 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
| 1,4-Dithiothreitol | DB04447 | EXPT01291 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 18977241 | Telomere lengths were calculated for 190 (82 men, 108 women) participants aged 79 years and associations with 384 SNPs, from 141 oxidative stress genes, identified 9 significant SNPS, of which those from 5 genes (GSTZ1, MSRA, NDUFA3, NDUFA8, VIM) had robust associations with physical aging biomarkers, respiratory function or grip strength |
Entries Per Page
Displaying Page of
