HCSGD entry for GSTM3
1. General information
| Official gene symbol | GSTM3 |
|---|---|
| Entrez ID | 2947 |
| Gene full name | glutathione S-transferase mu 3 (brain) |
| Other gene symbols | GST5 GSTB GSTM3-3 GTM3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004364 | Glutathione transferase activity | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006749 | Glutathione metabolic process | IDA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008065 | Establishment of blood-nerve barrier | TAS | biological_process |
| GO:0018916 | Nitrobenzene metabolic process | IDA | biological_process |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0042178 | Xenobiotic catabolic process | IDA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IDA IPI | molecular_function |
| GO:0043295 | Glutathione binding | IDA | molecular_function |
| GO:0043627 | Response to estrogen | IEP | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0070458 | Cellular detoxification of nitrogen compound | IDA | biological_process |
| GO:1901687 | Glutathione derivative biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1982020174 | 0.1303739979 | 0.8604134520 | 0.6949319563 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0552077969 |
| GSE13712_SHEAR | Down | -0.4968156516 |
| GSE13712_STATIC | Down | -0.5773488480 |
| GSE19018 | Down | -0.1568740315 |
| GSE19899_A1 | Down | -0.1106761128 |
| GSE19899_A2 | Down | -0.1505513022 |
| PubMed_21979375_A1 | Down | -0.8426240775 |
| PubMed_21979375_A2 | Down | -0.0103641579 |
| GSE35957 | Up | 0.4002998668 |
| GSE36640 | Up | 1.7292405917 |
| GSE54402 | Down | -0.5353958420 |
| GSE9593 | Up | 0.3901416142 |
| GSE43922 | Down | -0.1908803820 |
| GSE24585 | Up | 0.1099716320 |
| GSE37065 | Up | 0.1828589241 |
| GSE28863_A1 | Up | 0.2643969020 |
| GSE28863_A2 | Up | 0.9116049482 |
| GSE28863_A3 | Down | -0.2537312911 |
| GSE28863_A4 | Down | -0.0415182510 |
| GSE48662 | Up | 0.1433585580 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-122-5p | MIMAT0000421 | MIRT023377 | Proteomics | Functional MTI (Weak) | 21750653 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040526 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
