HCSGD entry for GSTA1
1. General information
| Official gene symbol | GSTA1 |
|---|---|
| Entrez ID | 2938 |
| Gene full name | glutathione S-transferase alpha 1 |
| Other gene symbols | GST2 GSTA1-1 GTH1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004364 | Glutathione transferase activity | IDA NAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006749 | Glutathione metabolic process | IDA | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008152 | Metabolic process | IC | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:1901687 | Glutathione derivative biosynthetic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8908845143 | 0.1223708674 | 0.9999902473 | 0.6713054606 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1427696409 |
| GSE13712_SHEAR | Down | -0.1865582920 |
| GSE13712_STATIC | Down | -0.0797372654 |
| GSE19018 | Up | 0.1379041010 |
| GSE19899_A1 | Up | 0.1220309336 |
| GSE19899_A2 | Down | -0.6972703444 |
| PubMed_21979375_A1 | Down | -0.4638997428 |
| PubMed_21979375_A2 | Down | -0.1336825957 |
| GSE35957 | Up | 0.0817524711 |
| GSE36640 | Up | 0.1925270041 |
| GSE54402 | Down | -0.6123759235 |
| GSE9593 | Up | 0.0188283457 |
| GSE43922 | Up | 0.0050151692 |
| GSE24585 | Up | 0.3059208580 |
| GSE37065 | Down | -0.1424111156 |
| GSE28863_A1 | Down | -0.2178244749 |
| GSE28863_A2 | Down | -0.2537407462 |
| GSE28863_A3 | Up | 0.0491590636 |
| GSE28863_A4 | Up | 0.1227997264 |
| GSE48662 | - | - |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glutathione | DB00143 | NUTR00029 | EXPT01650 |
| S-Hydroxycysteine | DB01915 | EXPT01035 | DB03398 |
| 2-Hydroxyethyl Disulfide | DB02486 | EXPT01723 |
| N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine | DB02943 | EXPT00404 |
| Glutathione Sulfonic Acid | DB03003 | EXPT01662 |
| S-Benzyl-Glutathione | DB03602 | EXPT01647 |
| S-Hexylglutathione | DB04132 | EXPT01664 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029138 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
