HCSGD entry for GRM8
1. General information
| Official gene symbol | GRM8 |
|---|---|
| Entrez ID | 2918 |
| Gene full name | glutamate receptor, metabotropic 8 |
| Other gene symbols | GLUR8 GPRC1H MGLUR8 mGlu8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001642 | Group III metabotropic glutamate receptor activity | IEA | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | IEA IMP | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007196 | Adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway | IMP | biological_process |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0007608 | Sensory perception of smell | IEA | biological_process |
| GO:0008066 | Glutamate receptor activity | IMP | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030818 | Negative regulation of cAMP biosynthetic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6800500931 | 0.9012846814 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0803913449 |
| GSE13712_SHEAR | Down | -0.1077106810 |
| GSE13712_STATIC | Up | 0.0643111501 |
| GSE19018 | Up | 0.0002336251 |
| GSE19899_A1 | Up | 0.0345937476 |
| GSE19899_A2 | Up | 0.0644208580 |
| PubMed_21979375_A1 | Up | 0.0360810270 |
| PubMed_21979375_A2 | Up | 0.0185053005 |
| GSE35957 | Up | 0.1880639680 |
| GSE36640 | Up | 0.1233995610 |
| GSE54402 | Down | -0.0170940192 |
| GSE9593 | Down | -0.0738566662 |
| GSE43922 | Up | 0.1016138733 |
| GSE24585 | Down | -0.0706750558 |
| GSE37065 | Down | -0.0418310709 |
| GSE28863_A1 | Down | -0.1046900008 |
| GSE28863_A2 | Up | 0.0956166389 |
| GSE28863_A3 | Up | 0.1962538101 |
| GSE28863_A4 | Up | 0.0019746764 |
| GSE48662 | Up | 0.0188984710 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Glutamic Acid | DB00142 | NUTR00027 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028921 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
